THE RELATIONSHIP BETWEEN ANTIRETROVIRAL THERAPY ADHERENCE AND QUALITY OF LIFE IN HIV/AIDS PATIENTS: A STUDY AT WELAS ASIH HOSPITAL

  • Saur Mian Sinaga Undergraduate Nursing Program, Faculty of Nursing, Institut Kesehatan Immanuel, Bandung, West Java, Indonesia
  • Agustiana Agustiana Department of Nursing, Faculty of Nursing, Institut Kesehatan Immanuel, Bandung, West Java, Indonesia
  • Herwinda Sinaga Department of Nursing, Faculty of Nursing, Institut Kesehatan Immanuel, Bandung, West Java, Indonesia

Abstract

One of the biggest global health concerns, Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) still presents a significant obstacle, even in Indonesia. Patient adherence to treatment is essential for antiretroviral therapy (ARV) to be successful. The purpose of this study was to investigate the relationship between ARV medication adherence and HIV/AIDS patients' quality of life. This study used a cross-sectional design and a quantitative design. 55 respondents in total were chosen by accident sampling from the population intended to be HIV/AIDS patients undergoing treatment at the Voluntary Counseling and Testing (VCT) Care, Support, and Treatment (CST) Clinic of RSUD Welas Asih. The World Health Organization Quality of Life – Brief Version (WHOQOL-BREF) instrument was used to measure quality of life, and the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire was used to evaluate medication adherence. The Spearman rank correlation test was used for both univariate and bivariate analyses of the data. The results indicated that the majority of respondents had a good quality of life and a high degree of adherence to ARV therapy. According to statistical analysis, there is a significant correlation (p <0.05) between ARV medication adherence and HIV/AIDS patients' quality of life. In conclusion, quality of life and treatment adherence are significantly correlated. In order to maintain treatment adherence and improve the quality of life for individuals living with HIV/AIDS, healthcare providers are advised to improve education and support.


 


Keywords: ARV Adherence, HIV/AIDS, quality of Life, Welas Asih Hospital.


DOI: 10.35990/mk.v9-ISGH.p127-136

References

Ministry of Health of the Republic of Indonesia. Report on the situation of HIV/AIDS in Indonesia 2020. Jakarta: Ministry of Health of the Republic of Indonesia; 2020.
2. Novianto A. Factors associated with ARV adherence in HIV/AIDS patients. Health Journal. 2020;7(2):95–103.
3. Djumadi A, Suryani D, Rachmawati R. Family support for adherence to ARV medication among people living with HIV. Journal of Health Sciences. 2023;14(1):45–52.
4. WHOQOL Group. WHOQOL-BREF: Introduction, administration, scoring and generic version. Geneva: World Health Organization; 2017.
5. Prameswari A. The relationship between ARV adherence and the quality of life of people living with HIV. Journal of Clinical Psychology and Mental Health. 2020;7(1):27–35.
6. Kemenkes RI. Berani Lindungi Diri, Kemenkes Targetkan Eliminasi HIV dan IMS Tahun 2030. Kemenkes RI. 2025 Jun.
7. Spiritia. Yayasan Spiritia. 2021. Pandemi Covid-19 Tenggelamkan Isu Epidemi HIV/AIDS Indonesia.
8. Kancana KS. Mengenal Terapi ARV: Mengelola Infeksi pada HIV/AIDS. Primaya Hospital. 2025 May.
9. Hamrahian SM, Maarouf OH, Fülöp T. A Critical Review of Medication Adherence in Hypertension: Barriers and Facilitators Clinicians Should Consider. Patient Prefer Adherence. 2022 Oct;Volume 16:2749–57. doi:10.2147/PPA.S368784
10. Arnandes Putra A, Triana V, Siswati S. HUBUNGAN KEPATUHAN MINUM OBAT ANTIRETROVIRAL (ARV) DENGAN KUALITAS HIDUP PADA LAKI-LAKI PENDERITA HIV : STUDI CROSS -SECTIONAL. PREPOTIF : JURNAL KESEHATAN MASYARAKAT. 2026 Mar 6;10(1):710–8. doi:10.31004/prepotif.v10i1.55563
11. Kemenkes RI. HIV ada Obatnya, ARV Disediakan Gratis Oleh Pemerintah. Kemenkes RI; 2017 Dec.
12. De las Cuevas C, Peñate W. Psychometric properties of the eight-item Morisky Medication Adherence Scale (MMAS-8) in a psychiatric outpatient setting. International Journal of Clinical and Health Psychology. 2015 May;15(2):121–9. doi:10.1016/j.ijchp.2014.11.003
13. Adejumo OA, Malee KM, Ryscavage P, Hunter SJ, Taiwo BO. Contemporary issues on the epidemiology and antiretroviral adherence of HIV-infected adolescents in sub-Saharan Africa: A narrative review. J Int AIDS Soc. 2023;18(1).
14. Suryanto Y, Nurjanah U. KEPATUHAN MINUM OBAT ANTI RETRO VIRAL (ARV) PADA PASIEN HIV/AIDS. Jurnal Ilmu Keperawatan Indonesia (JIKPI). 2021 Mar 17;2(1):14–22. doi:10.57084/jikpi.v2i1.635
15. Safitri A. Analysis of quality of life among HIV/AIDS patients. J Health Res. 2020;5(2):44–50.
16. Omenogor DA, Omonaiye O. The impact of antiretroviral therapy on the quality of life of HIV patients. Journal of Health Sciences. 2023;7(2):112–20.
17. Handayani S. The relationship between adherence to ARV medication and the quality of life of HIV/AIDS patients. J Public Health (Bangkok). 2023;8(3):211–8.
18. Joulaei H. Quality of life and adherence to treatment in HIV-infected patients. Journal AIDS Care. 2023;33(5):600–8.
19. Nurjanah S, Yuliana, Prasetyo. Determinants of Quality of Life in HIV/AIDS Patients: A Cross-Sectional Study. Journal of Indonesian Health Policy. 2023;8(1):55–62.
20. Sitorus RJ, Anwar C, Purba I, Natalia M. Determinan Kadar Cluster Diferensiasi 4 (CD4) pada Orang dengan HIV/AIDS. Jurnal Kesehatan. 2021 Apr 29;12(1):116–22. doi:10.26630/jk.v12i1.2423
Published
2026-06-30
How to Cite
SINAGA, Saur Mian; AGUSTIANA, Agustiana; SINAGA, Herwinda. THE RELATIONSHIP BETWEEN ANTIRETROVIRAL THERAPY ADHERENCE AND QUALITY OF LIFE IN HIV/AIDS PATIENTS: A STUDY AT WELAS ASIH HOSPITAL. Medika Kartika : Jurnal Kedokteran dan Kesehatan, [S.l.], v. 9, p. 127-136, june 2026. ISSN 2655-6537. Available at: <http://medikakartika.unjani.ac.id/medikakartika/index.php/mk/article/view/1655>. Date accessed: 20 sep. 2026.